Our Publications


1. Savostyanov G.A. The base of structural histology. Spatial organization of epithelia. Sankt Petersburg, Nauka, 2005, 375 p. (Read in Russian).


Savost'yanov G. A. Theoretical and Evolutionary Biology: Structural Defects in Regular Cell Mosaics and Their Putative Functional Significance // Paleontological Journal, 2014, Vol. 48, No. 11, pp. 1152-1162. DOI: 10.1134/S0031030114110100

1. Savost`yanov G.A. Theoretical analysis and formal description of division of labour as an invariant in development of various community. // Evolution: Aspects of modern evolutionism. Eds. L.E. Grinin, A.V. Korotaev, A.V. Markov, Moskow, 2012, p. 81-85. (Read in Russian).

2. Savost`yanov G.A. The Origin of Elementary Units of Multicellularity and Development of a Spatial Organization of Cell Layers // Izv Akad Nauk Ser Biol. 2012 Mar-Apr;(2):164-74. ISSN 1062-3590, Biology Bulletin, 2012, Vol. 39, No. 2, pp. 127136. Pleiades Publishing, Inc., 2012. Medline abstract. Read this article in Russian. Also read this article in English.

3. Savost`yanov G.A. Modeling of processes of specialization and integration as a basis for development of multicellularity. // Zhurnal Evol. Biokhim. i Fiziol., 2010, Vol. 46, No. 6, pp. 514521. Medline abstract. Read the full text in English (Journal of Evolutionary Biochemistry and Physiology, 2010, V. 46, N 6, pp. 613-621).

4. Savost`yanov G.A. Towards the theoretical biology of multicellularity development. / Charles Darwin and modern biology. // Proceedings of the International Academic Conference 2123 September, 2009, Saint-Petersburg. Nestor-Historia, Saint-Petersburg, 2010, p. 534-541. (Read in Russian).

5. Magnitskaya Ye.G., Grefner N.M., Golubeva T.B., Vorobyov A.V., Levchenko V.F., Savostyanov G.A. Epithelium 3D structure transformation during development, with bird basilar papilla sensory epithelium as an example. // Sensory Systems, 2009, v. 23, No 4, p. 334-345. (Read in Russian).

6. Savostyanov G.A. Tissue modules as a base of theoretical histology. / "Meristems, Modules, Shoots in Different Plant Kingdoms of Living Organisms" Proc. XI Intern. Workshop on Theoretical Plant Morphology (Tver, Russia, 10-16 November, 2008). // Bulletin of Tver State University, 2008, 25(85), Biology&Ecology series, Isue 9, 2008, p. 234-246. (Read in Russian).

7. Savostyanova E.G., Vorobyov A.V., Grefner N.M., Levchenko V.F. and Savostyanov G.A. Towards the computational three-dimensional histology. Application of computer models to the reconstruction of the biological tissue three-dimensional structure with bird sensory cochlear epithelium as an example // Morphology, 2007, v 131, No 1, p. 8-17 (in Russ). Medline abstract

8. Savostyanov G.A., Grefner N.M., Golubeva T.B., and Savostyanova E.G. Three dimensional organization of epithelia of the AB2 composition by the example of the cochlea sensory epithelium of birds // Zhurnal Evol. Biokhim. i Fiziol., 2005, vol. 41, No. 5, pp. 457 - 464. Medline abstract. Read the full text in English (J. of Evolutionary Biochemistry and Physiology, 2005, V.41, N5, pp.570-579).

9. Savostyanov G. A. Principles of spatial organization of cellular sheets. // Biophysics 2001 (a), V. 46, N 3, pp. 512-517. Medline abstract. Read the full text in English (Biophysics, V.46, N3, 2001, pp.487-493).

10. Savostyanov G. A. Theory of spatial organization of epithelial layers (using neuroepithelia as an example) // Morphology (in Russian), 2001 (b), V. 120, N 5, pp 18-30. Medline abstract.

11. Savostyanov G.A. Topological and geometrical simulation of 3-D structure of insect appositional and superpositional retina. // Sensory systems, 2001 (c), V. 15, N 2, pp. 121 - 132. (in Russian)

12. Savostyanov G.A., Grefner N.M., Golubeva T.B., and Savostyanova E.G. The 3-dimensional organization of the sensory epithelium of the cochlea in birds // Morphology, 2000, v 117, No 2, p. 62-68 (in Russ). Medline abstract

13. Savost`yanov G.A., Grefner N.M. Three-dimensional histoarchitectonics of the larval epidermis of the grass frog. Ontogenez, 1998, v. 29, 1, p. 31-37. Medline abstract

14. Savostyanov G.A.,. Modelling of the 3-dimensional structure of the epithelia, constructed of bi-, tri and tetracellular modules. // Morfologiia, 1998, v. 113, N 2, pp. 7-20 (in Russ.). Medline abstract

15. Grefner N.M., G. A. Savostyanov, V.V. Khudoley. The study of cell mozaics of ectodermal tumors in embryos of Rana temporaria L using a scanning electron microscope. // Experimental Oncology, 1997, v. 19, 4, p. 289 - 295. (in Russ.).

16. Savostyanov G.A. A model of the spatial organization of double-row (pseudostratified) epithelium (a topical article) //J. of Evolutionary Biochemistry and Physiology (Zh. Evol. Biokhim. Fiziol.), 1994, V. 30, N 5, pp. 625 - 631. Medline abstract

17. Savostyanov G.A., Grefner N.M. The translation symmetry in cell mosaics of amphibian embryonic ectoderm as a manifestation of their modular structure // Izv Akad Nauk Ser Biol. 1993, N 6, pp. 805 - 813. Medline abstract

18. Savostyanov G.A. Theory of mosaics of the squamous epithelium // Arkh. Anat. Gistol. Embriol. 1991, v.100, N 6, pp. 5 - 27 (in Russ). Medline abstract

19. Savostyanov G.A. Experience in the formation of a deductive theory of specialization and integration of cells in phylo-, onto- and pathogenesis // Arkh Anat Gistol Embriol. 1989 (a), v. 96, N 2, pp. 78 - 93 (in Russ.). Medline abstract

20. Savostyanov G.A. The functional significance and stoichiometry of cellular mosaics of squamous epithelial cells. // Dokl Akad Nauk SSSR. Proceedings of the Academy of Sciences, USSR. 1989 (b), V.307, Nos. 1 - 6, July-August, pp.1483 - 1486. Medline abstract

21. Savostyanov G.A. Experiment in the economic evaluation of the results of cellular specialization and integration in the development of multicellular organisms. The elements of bioeconomics. // Zh Obshch Biol. 1980, V. 41(1), pp. 56-67. Medline abstract

22. Savostyanov G.A. On some elementary acts and laws of development. Elements of structural biology. // J. General Biology (in Russian), 1977, V. 38, N 2, pp.167 - 181.

23. Savostyanov G.A. An axiomatic approach to the study of specialization and integration as the basis for multicellularity. // Cytology (Tcitology, in Russian), 1976, V 18, N 5, pp.611 - 619.


1. Magnitskaya E.G., Golubeva T.B., Grefner N.M., Vorobyov A.V., Savostyanov G.A. Computer simulation and confocal microscopy for 3D reconstruction of the epithelial tissues / Modern microscopy techniques in biology and medicine. // Proc. Int. conf., St. Petersburg State Univ., Leica microsistems, St. Petersburg, 2009, P. 19-20. Read it

2. G. A. Savostyanov, A.V. Vorobyov, N.M. Grefner, Y.G. Magnitskaja. Theoretical and experimental basis of tissue engineering. // Saint-Petersburg International workshop on NanoBioTechnologies, 27-29 November 2006. P. 16

3. G. A. Savostianov, A.V. Vorobiev. Computer simulation of 3D tissue structure. // Computer applications in scientific researches IVTN-2003, Moscow 2003, P. 16. Read it

4. G. A. Savostyanov, N.M. Grefner, O.F. Lutskaya, E. G. Savostyanova. Morphogenesis of 3-D Structure of Epithelia and principles of their Reconstruction. Proceedings of the International Symposium on "TEORETICAL BIOPHYSICS AND BIOMATHEMATICS" Inner Mongolia University Press, Hohhot, 1997, p. 194 Read it

5. G. A. Savostyanov, Grefner N.M., Lutskaya O.F., Symmetry of epithelial tissues as a result of self-organisation procecces. The International Conference on Nonlinear Dynamics and Chaos. Applications in Physics, Biology and Medicine ICND-96. Saratov State University, Saratov, Russia, 1996, p. 158. Read it

6. G. A. Savostyanov. Symmetry of spatial organization of epithelia. Proc. International Workshop on Information Processing in Cells and Tissues. Liverpool 1995, p. 614-616. Read it

The publications we have used

1. Carragher B., Smith P.R. Advances in Computational Image Processing for Microscopy //J. Structural Biology 1996, 116, 1, 2-8 Medline abstract

2. Caveney S. Compound Eyes. in: "Microscopic Anatomy of Invertebrates". 1998. V. 11B: Insecta. P. 423 - 449. One Source 4 Media, Inc.

3. Chimento T.C., Doshay D.G., Ross M.D. Compartmental modeling of rat macular primary afferents from three-dimensional reconstructions of transmission electron micrographs of serial sections. // J. Neurophysiology, 1994, v. 71, N 5, pp. 1883-1896. Medline abstract

4. Dormer K.J. Fundamental tissue geometry for biologist. Cambridge University Press, London, 1980, 150 p. An-Najah Libraries

5. Engstrom B. A. Borg E. Cochlear morphology in relation to loss of behavioral, electrophysiological and middle ear reflex threshoulds after exposure to noise. // Acta Otolaringol. Suppl. 1983, v. 402, p. 5 - 23. Medline abstract

6. Esau K. The seminal plants anatomy. Translated by Word Press, Moscow. 1980.

7. Fehon R.G., Johansen K., Rebay I., Artavanis-Tsakonas S. Complex cellular and subcellular regulation of Nothc expression during embryonic and imaginal development of Drosophila: implication for Notch function. // J. Cell Biology, 1991, v. 113, N. 3, p. 657 - 669. Medline abstract

8. Goodyear R. and Richardson G. Pattern Formation in the Basilar Papilla: Evidence for Cell Rearrangement // J. Neurosci. 1997, 17(16), 6289 - 6301. Medline abstract

9. Honda H., Yamanaka H. A. Egushi G. Transformation of a polygonal cellular pattern during sexual maturation of the avian oviduct epithelium: computer simulation. // J. Embryol. Exper. Morphol. 1986, v. 98, p. 1 - 19. Medline abstract

10. Landstrom U. On differentiation of prospective ectoderm to a ciliated cell patern in embryos of Ambystoma mexicanum. // J. Embryol. Exper. Morphol. 1977, v.41, p.23-32. Medline abstract

11. Lewis F.T. The shape of cell as a mathematical problem // Amer. scientist, 1946, v. 34, No 3, p. 359-369.

12. Loew E. R., Govardovskii V. I., Pohlich P., Szel A. Microspectrophotometric and immunocitochemical identification of ultraviolet photoreceptors in geckos // Visual Neurosci. 1996. Vol. 13, P. 247-256. Medline abstract

13. Maresin V. M. Spatial organization of embryogenesis. Nauka, 1990. (in Russ.).

14. Miller D.T., Cagan R.L. Local induction of patterning and programmed cell death in the developing Drosophila retina // Development 1998, 125(12), pp. 2327 - 2335. Medline abstract

15. Nagano T. a. Suzuki F. Cell junctions in the seminiferous tubule and the excurrent duct of the testis: freeze-fracture studies. // Int. Rev. Cytol. 1983, v.81, p. 163 - 190. Medline abstract

16. Ready D.F., Hanson T.E. and Benzer S. Development of the Drosophila Retina, a Neurocrystalline Lattice. // Dev. Biol. 1976. V. 53. N 2. P. 217 - 240. Medline abstract

17. Russ J.C. The Image Processing. CRC Press, Boca Raton, Ann Arbor, London, Tokyo, 1995, 674 p.

18. Smolyaninov V.V. Mathematical models of biological tissues. // Nauka, 1980. (in russ.).

19. Wolff T., Ready D.F. Cell Death in Normal and Rough eye mutants of Drosophila // Development 1991. V. 113. N 3. P. 825 - 839. Medline abstract

Back to the Homepage